Busch claimed NASCAR win No.98 in Thursday's Camping World Truck Series event and then No.99 in Saturday's Sprint Cup Series race.
His next win will make him just the third NASCAR driver with 100 or more victories to his credit. Richard Petty holds the record with 200 wins, followed by David Pearson with 106. One of Pearson's victories came in a Nationwide race in 1982 at Rockingham.
To date, Busch's NASCAR win column includes 22 in Sprint Cup, 48 Nationwide and 29 in trucks.
"Whenever the next one is, I'll be cherishing it just as much as I did the last one," Busch said. "To me, I don't want to wait that long for win 100."